2128 Experimental model of proliferative vitreoretinopathy and inhibition by liposome-encapsulated 5-fluorouridine
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منابع مشابه
2128 Experimental model of proliferative vitreoretinopathy and inhibition by liposome-encapsulated 5-fluorouridine
Pm-mme. The function of RPE is well known in PVR. Pharmacologic agents have been extensively shldied both experimentally and clinically. Few reports have derailled the interactions of a”timitctic drugs on the microtubule network. The aim of this study is to visualize by indirect immunofluwescence the modification of the microtubule network of cultured pig RPE cells by colchicina and taxol. Yetb...
متن کاملP 398 Title: Experimental retinal toxicity of intravitreal injection of liposome encapsulated 5-fluorouridine
Eurppse : To evaluate the presence of Neuron Specific Enolase (NSE) in subretinal fluid (SRF? as a uotential marker for retinal damaee and to correlate these b&Vets ‘tith r&al detachment (RD) pzmmwem kS.E is a reliablemarkerofneuronallysisintbecerebro-~fluidinbraindamage. Levels of NSE in the aqueous humour are also elevated in retiwblastoma NSEhaskdetectedinalllayenofnmmal humanretinaexcepth4u...
متن کاملP 191 Corneal endothelial toxicity of liposome encapsulated 5-fluorouridine in rabbits
P"rpse: To investigate the clinical and histological toxicity of the exposure of the :rabbit cornea1 endothelium to anterior chamber injection of liposome-encapsulated 5-fluorouridine (LS-FUR) at concentrations of 1 mg/ml and 0.38 mg/ml and intravitreal injection of I.5FUR at 1 mg/ml. M*thOdS : A total of 12 New Zealand white rabbits were divided in three groups: A) Anterror chamber rnjectian o...
متن کاملProliferative vitreoretinopathy.
PURPOSE. The migration, proliferation, differentiation, and adhesion of cells and other cellular functions are influenced by the surrounding extracellular matrix, in normal and wound-healing conditions. The matrix metalloproteinases (MMPs) are a family of enzymes that degrade and remodel the extracellular matrix and, thus, play a central role in the wound-healing process. Proliferative vitreore...
متن کاملA new model of proliferative vitreoretinopathy.
PURPOSE To design a new model of proliferative vitreoretinopathy (PVR) that would not rely on the addition of exogenous cells. The release of endogenous cells from surrounding attachments seems to be an early event in the pathogenesis of PVR. Because the proteolytic enzyme dispase dissociates tissues, the hypothesis was that an intraocular injection of dispase could trigger events that would ca...
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ژورنال
عنوان ژورنال: Vision Research
سال: 1995
ISSN: 0042-6989
DOI: 10.1016/0042-6989(95)90140-x